Stephen N Greszler

13PUBLICATIONS
18CO-AUTHORS
Chemical engineering designBiologically active moleculesCarbon capture engineering (excl. sequestration)Cheminformatics and quantitative structure-activity relationshipsOrganometallic chemistry
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Publications (13)

|May 19, 2025
Asymmetric Synthesis of Small Molecule Inhibitors of IL-17A via Crystallization-Induced Diastereoselective Strecker Reaction.

Stephen N Greszler, Gang Zhao, Michael A Leitch

|Apr 04, 2024
Discovery of Small Molecule Interleukin 17A Inhibitors with Novel Binding Mode and Stoichiometry: Optimization of DNA-Encoded Chemical Library Hits to In Vivo Active Compounds.

Ashley L Ramos, Eric R Goedken, Kristine E Frank

|Mar 25, 2024
Discovery of GLPG2737, a Potent Type 2 Corrector of CFTR for the Treatment of Cystic Fibrosis in Combination with a Potentiator and a Type 1 Co-corrector.

Mathieu Pizzonero, Rhalid Akkari, Xavier Bock

|Dec 12, 2022
Synthesis of A-9758, an Inverse Agonist of Retinoic Acid-Related Orphan Receptor γt.

Christopher C Marvin, Stephen N Greszler, Bhadra H Shelat

|Sep 30, 2022
Enabling Asymmetric Synthesis of ABBV-3748, a Corrector Compound for the Treatment of Cystic Fibrosis.

Stephen N Greszler, Gang Zhao, Bhadra Shelat

|Dec 23, 2021
Lithioarene Cycliacylation and Pd-Catalyzed Aminoethylation/Cyclization to Access Electronically Diverse Saturated Isoquinoline Derivatives.

Marek Buchman, Elliot P Farney, Stephen N Greszler

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Frequent Collaborators

8 joint publications

Eric A Voight

2 joint publications

Matthew P Webster

2 joint publications

Kristine E Frank

2 joint publications

Ashley L Ramos