Diego E Sastre

5PUBLICATIONS
30CO-AUTHORS
Applied immunology (incl. antibody engineering, xenotransplantation and t-cell therapies)Epigenetics (incl. genome methylation and epigenomics)Biocatalysis and enzyme technologyBiomolecular modelling and design
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (5)

|Dec 12, 2025
Asymmetrically glycosylated IgG1 antibodies are universal and drive human disease.

Tala Azzam, Stylianos Bournazos, Hasret Gunduz

|Jul 31, 2025
Molecular basis of Fab-dependent IgA antibody recognition by gut-bacterial metallopeptidases.

María Ángeles Márquez-Moñino, Ana Martínez Gascueña, Tala Azzam

|Jul 03, 2025
The mechanistic basis for interprotomer deglycosylation of antibodies by corynebacterial IgG-specific endoglycosidases.

Diego E Sastre, Stylianos Bournazos, Maros Huliciak

|Jun 15, 2024
Human gut microbes express functionally distinct endoglycosidases to metabolize the same N-glycan substrate.

Diego E Sastre, Nazneen Sultana, Marcos V A S Navarro

|Apr 10, 2024
Combinatorially restricted computational design of protein-protein interfaces to produce IgG heterodimers.

Tala Azzam, Jonathan J Du, Maria W Flowers

Pageof 1

Frequent Collaborators

4 joint publications

Tala Azzam

4 joint publications

Eric J Sundberg

3 joint publications

Jonathan J Du

3 joint publications

Maria W Flowers