Yih-Chih Chan

11PUBLICATIONS
113CO-AUTHORS
Nanoscale characterisationGene and molecular therapyEpigenetics (incl. genome methylation and epigenomics)Molecular targetsMedical molecular engineering of nucleic acids and proteins
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (11)

|Jul 21, 2026
SUMOylation enhances DNMT1 function to repress mega-intergenic RNAs and viral mimicry.

|Jun 19, 2025
Catalytic Inhibition of KAT6/KAT7 Enhances the Efficacy and Overcomes Primary and Acquired Resistance to Menin Inhibitors in MLL Leukemia.

Shellaina J V Gordon, Florian Perner, Laura MacPherson

|Sep 07, 2023
CRISPR-ChIP reveals selective regulation of H3K79me2 by Menin in MLL leukemia.

Omer Gilan, Laure Talarmain, Charles C Bell

|Aug 07, 2023
Inhibition of METTL3 Results in a Cell-Intrinsic Interferon Response That Enhances Antitumor Immunity.

Andrew A Guirguis, Yaara Ofir-Rosenfeld, Kathy Knezevic

|Jan 12, 2023
Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes.

Christina E Sparbier, Andrea Gillespie, Juliana Gomez

|Dec 09, 2021
Non-genetic determinants of malignant clonal fitness at single-cell resolution.

Katie A Fennell, Dane Vassiliadis, Enid Y N Lam

Pageof 2

Frequent Collaborators

11 joint publications

Mark A Dawson

8 joint publications

Enid Yn Lam

6 joint publications

Sarah-Jane Dawson

5 joint publications

Charles C Bell