Severin Lechner

9PUBLICATIONS
78CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsCharacterisation of biological macromoleculesPharmacogenomicsGene expression (incl. microarray and other genome-wide approaches)Medical biochemistry - lipids
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (9)

|May 09, 2025
Serendipitous and Systematic Chemoproteomic Discovery of MBLAC2, HINT1, and NME1-4 Inhibitors from Histone Deacetylase-Targeting Pharmacophores.

Severin Lechner, Shuyao Sha, Jigar Paras Sethiya

|Nov 25, 2024
Critical assessment of LC3/GABARAP ligands used for degrader development and ligandability of LC3/GABARAP binding pockets.

Martin P Schwalm, Johannes Dopfer, Adarsh Kumar

|May 07, 2024
Decrypting the molecular basis of cellular drug phenotypes by dose-resolved expression proteomics.

Stephan Eckert, Nicola Berner, Karl Kramer

|Nov 02, 2023
A region-resolved proteomic map of the human brain enabled by high-throughput proteomics.

Johanna Tüshaus, Amirhossein Sakhteman, Severin Lechner

|Jun 15, 2023
Chemoproteomic target deconvolution reveals Histone Deacetylases as targets of (R)-lipoic acid.

Severin Lechner, Raphael R Steimbach, Longlong Wang

|Mar 17, 2023
Decrypting drug actions and protein modifications by dose- and time-resolved proteomics.

Jana Zecha, Florian P Bayer, Svenja Wiechmann

Pageof 2

Frequent Collaborators

9 joint publications

Bernhard Kuster

6 joint publications

Guillaume Médard

3 joint publications

Christian Grätz

3 joint publications

Raphael R Steimbach