David A Lomas

13PUBLICATIONS
65CO-AUTHORS
BiomaterialsFood engineeringPolymerisation mechanismsPowder and particle technologyOccupational epidemiology
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Publications (13)

|May 01, 2026
BMN 349, a small molecule inhibitor of Z alpha-1 antitrypsin polymerization, increases secretion and reduces intrahepatic inclusions in a mouse model of disease.

|Nov 13, 2025
The mechanism of pathogenic α<sub>1</sub>-antitrypsin aggregation in the human liver.

Ibrahim Aldobiyan, Emma L K Elliston, Narinder Heyer-Chauhan

|May 07, 2025
High-resolution characterization of ex vivo AAT polymers by solution-state NMR spectroscopy.

Sarah M Lowen, Christopher A Waudby, Alistair M Jagger

|Jan 27, 2025
Assessing Inflammatory Protein Biomarkers in COPD Subjects with and without Alpha-1 Antitrypsin Deficiency.

Matthew Moll, Brian D Hobbs, Katherine A Pratte

|Jan 08, 2025
Identification of an exosite at the neutrophil elastase/alpha-1-antitrypsin interface.

Roberto Gangemi, Mattia Bignotti, Andrea Denardo

|Jul 02, 2024
Reduction of Z alpha-1 antitrypsin polymers in human iPSC-hepatocytes and mice by LRRK2 inhibitors.

Deniz Kent, Soon Seng Ng, Adam M Syanda

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Frequent Collaborators

10 joint publications

James A Irving

4 joint publications

Riccardo Ronzoni

3 joint publications

Alistair M Jagger

2 joint publications

Ibrahim Aldobiyan