Karl Dane Wittrup

23PUBLICATIONS
96CO-AUTHORS
Cancer therapy (excl. chemotherapy and radiation therapy)Applied immunology (incl. antibody engineering, xenotransplantation and t-cell therapies)Industrial molecular engineering of nucleic acids and proteinsRadiation therapyMolecular targets
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Publications (23)

|Aug 25, 2025
Directed evolution-based discovery of ligands for in vivo restimulation of chimeric antigen receptor T cells.

Tomasz M Grzywa, Alexandra Neeser, Ranjani Ramasubramanian

|Oct 09, 2024
Tumor Integrin-Targeted Glucose Oxidase Enzyme Promotes ROS-Mediated Cell Death that Combines with Interferon Alpha Therapy for Tumor Control.

Jordan A Stinson, Allison Sheen, Brianna M Lax

|Jul 09, 2024
Tumor-Localized Interleukin-2 and Interleukin-12 Combine with Radiation Therapy to Safely Potentiate Regression of Advanced Malignant Melanoma in Pet Dogs.

Jordan A Stinson, Matheus Moreno P Barbosa, Allison Sheen

|Jun 06, 2024
CLN-617 Retains IL2 and IL12 in Injected Tumors to Drive Robust and Systemic Immune-Mediated Antitumor Activity.

Naveen K Mehta, Kavya Rakhra, Kristan A Meetze

|Mar 01, 2024
CD8+ T cell priming that is required for curative intratumorally anchored anti-4-1BB immunotherapy is constrained by Tregs.

Joseph R Palmeri, Brianna M Lax, Joshua M Peters

|Jan 03, 2024
A Novel Gain-of-Signal Assay to Detect Targeted Protein Degradation.

Megan Hoffman, Keith Ming Hong Cheah, K Dane Wittrup

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Frequent Collaborators

10 joint publications

Noor Momin

8 joint publications

Darrell J Irvine

6 joint publications

Emi A Lutz

4 joint publications

Stefani Spranger