Karen A Kirby

21PUBLICATIONS
58CO-AUTHORS
PharmacogenomicsStructural properties of condensed matterFlight dynamicsApplied immunology (incl. antibody engineering, xenotransplantation and t-cell therapies)Powder and particle technology
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Publications (21)

|Aug 20, 2026
Breakthrough Design of Highly Potent Antivirals Against Wild-Type HIV-1 and Lenacapavir-Resistant M66I Variant.

|Jul 07, 2026
HIV-1 capsid interactions with Nuclear Pore Complex components support nuclear entry via affinity gradient.

|Jun 22, 2026
Structural and Mechanistic Basis of F227C-Mediated Hypersusceptibility to Islatravir in HIV-1 Reverse Transcriptase.

|Jun 12, 2026
Unraveling the Mechanism of HIV-1 Hypersusceptibility to Tenofovir Imparted by Islatravir Resistance Mutations.

|Apr 17, 2026
Structural Basis of Polypurine Track Strand Displacement by HIV-1 Reverse Transcriptase.

|Mar 27, 2026
Damaging the conical morphology of HIV-1 capsid by targeting the FG-binding pocket and disfavoring pentameric subunits needed for core closure.

William M McFadden, Karen A Kirby, Zachary C Lorson

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Frequent Collaborators

13 joint publications

Stefan G Sarafianos

8 joint publications

Zachary C Lorson

7 joint publications

William M McFadden

7 joint publications

Zhengqiang Wang