Daniel T Gewirth
4PUBLICATIONS
5CO-AUTHORS
Get your video featured.
Publish with JoVEGet your video featured.
Publish with JoVE
Publications (4)
Sort by Publication Date:
|Oct 30, 2024
Selective Inhibition of hsp90 Paralogs: Uncovering the Role of Helix 1 in Grp94-Selective Ligand Binding.Nanette L S Que, Paul M Seidler, Wen J Aw
|Sep 11, 2019
NECA derivatives exploit the paralog-specific properties of the site 3 side pocket of Grp94, the endoplasmic reticulum Hsp90.John D Huck, Nanette L S Que, Robert M Immormino
|May 30, 2019
Structures of Hsp90α and Hsp90β bound to a purine-scaffold inhibitor reveal an exploitable residue for drug selectivity.John D Huck, Nanette L S Que, Sahil Sharma
|Mar 13, 2018
Structure Based Design of a Grp94-Selective Inhibitor: Exploiting a Key Residue in Grp94 To Optimize Paralog-Selective Binding.Nanette L S Que, Vincent M Crowley, Adam S Duerfeldt
Pageof 1
