Xin Chen

7PUBLICATIONS
13CO-AUTHORS
Chemical engineering designMolecular targetsBiologically active moleculesGene and molecular therapy
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Publications (7)

|Sep 15, 2026
Covalent allosteric inhibition of AARS1 lactyltransferase.

|Aug 13, 2026
Structure-Based Discovery of JN210 as a Potent Dual DCN1/HDAC Inhibitor for the Treatment of Nonsmall Cell Lung Cancer.

|Nov 20, 2025
Fragment-Based Screening of NSD2-PWWP1 Identifies Novel Covalent Allosteric Ligands That Diminish Methyllysine and DNA Binding Abilities of NSD2.

Yunyuan Huang, Yanxi Li, Xin Chen

|May 09, 2025
Discovery of Non-antibacterial Enrofloxacin Derivatives with Emerging Antiaging Effects through Drug Repurposing and Secondary Development.

Sicong Qiao, Xin Chen, Youyou Chen

|Sep 11, 2024
Novel Combination Therapy for Heart Failure: Trimebutine-Methoxsalen Identified through Synergistic Network Virtual Screening and Experimental Validation.

Yunyuan Huang, Xin Chen, Jin Yang

|Nov 02, 2022
A senolysis-based theragnostic prodrug strategy towards chronic renal failure.

Yihe Song, Xinming Li, Donglei Shi

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Frequent Collaborators

4 joint publications

Jian Li

4 joint publications

Yunyuan Huang

3 joint publications

Donglei Shi

2 joint publications

Jinrong Min