Takao Yamaguchi

17PUBLICATIONS
18CO-AUTHORS
GlycoconjugatesProteins and peptidesBiologically active moleculesMolecular medicineCharacterisation of biological macromolecules
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Publications (17)

|Jun 18, 2026
An improved guanidine protecting group for the efficient synthesis of GuNA[t-Bu]-modified antisense oligonucleotides.

|Jan 31, 2026
Genetic Encoding of a Trifunctional Photo-Cross-Linker with a Cleavable Alkyl Ester Moiety.

Masahiro Takayama, Tomoya Tsubota, Takao Yamaguchi

|Nov 07, 2025
Development of Synthetic Routes to 2'-O,4'-C-Spirocyclopentylene-Bridged Nucleic Acids: Thymidine, Guanosine, and Adenosine.

Riku Kumagai, Riko Yamada, Takao Yamaguchi

|Oct 31, 2025
Cycloalkane Incorporation Into the 2',4'-Bridge of Locked Nucleic Acid: Enhancing Nuclease Stability, Reducing Phosphorothioate Modifications, and Lowering Hepatotoxicity in Antisense Oligonucleotides.

Takao Yamaguchi, Hibiki Komine, Takaya Sugiura

|Aug 06, 2025
Phthalimide: a potential warhead for switchable and bioorthogonal conjugation.

Kosuke Chiba, Takumi Yoshida, Kana Okada

|Jul 31, 2024
Separation and Characterization of Therapeutic Oligonucleotide Isomer Impurities by Cyclic Ion Mobility Mass Spectrometry.

Shogo Omuro, Takao Yamaguchi, Taiji Kawase

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Frequent Collaborators

17 joint publications

Satoshi Obika

3 joint publications

Kosuke Chiba

1 joint publications

Kunihiko Morihiro

1 joint publications

Takumi Okuda