Robert Elsby

2PUBLICATIONS
0CO-AUTHORS
PharmacogenomicsGene and molecular therapy
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (2)

|Feb 22, 2023
Mechanistic in vitro studies indicate that the clinical drug-drug interactions between protease inhibitors and rosuvastatin are driven by inhibition of intestinal BCRP and hepatic OATP1B1 with minimal contribution from OATP1B3, NTCP and OAT3.

Robert Elsby, Hannah Coghlan, Jacob Edgerton

|Oct 04, 2017
Mechanistic in vitro studies confirm that inhibition of the renal apical efflux transporter multidrug and toxin extrusion (MATE) 1, and not altered absorption, underlies the increased metformin exposure observed in clinical interactions with cimetidine, trimethoprim or pyrimethamine.

Robert Elsby, Stephen Chidlaw, Samuel Outteridge

Pageof 1

Frequent Collaborators