Dylan J Nikkel

9PUBLICATIONS
3CO-AUTHORS
Reaction engineering (excl. nuclear reactions)Molecular targetsInstrumental methods (excl. immunological and bioassay methods)EnzymesSynthetic biology
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (9)

|Jul 04, 2026
How Do DICER1 Syndrome Mutations Disrupt Catalysis? Unveiling Dicer Metal Binding Architecture and Mechanism of Action Using MD Simulations and QM/MM Calculations.

|May 27, 2026
Insights into the Debated Lyase Mechanism of Bifunctional DNA Glycosylases from MD and QM/MM MD Simulations: The Case Study of DNA Oxidative Damage Repair by Human 8-Oxoguanine DNA Glycosylase.

|Mar 24, 2026
Decoding the Catalytic Strategy for DNA Alkylation Repair by AlkA: Insights from MD Simulations and QM/MM Calculations.

Dylan J Nikkel, Basel Mansour, Ryan Fjordbotten

|Oct 30, 2025
Unlocking the chemistry facilitated by enzymes that process nucleic acids using quantum mechanical and combined quantum mechanics-molecular mechanics techniques.

Dylan J Nikkel, Stacey D Wetmore

|Dec 25, 2024
How Can One Metal Power Nucleic Acid Phosphodiester Bond Cleavage by a Nuclease? Multiscale Computational Studies Highlight a Diverse Mechanistic Landscape.

Dylan J Nikkel, Rajwinder Kaur, Stacey D Wetmore

|Oct 03, 2024
Mechanism of Nucleic Acid Phosphodiester Bond Cleavage by Human Endonuclease V: MD and QM/MM Calculations Reveal a Versatile Metal Dependence.

Rajwinder Kaur, Dylan J Nikkel, Stacey D Wetmore

Pageof 2

Frequent Collaborators

9 joint publications

Stacey D Wetmore

4 joint publications

Rajwinder Kaur

2 joint publications

Mohamed M Aboelnga