Reinhard Lührmann

8PUBLICATIONS
32CO-AUTHORS
Catalysis and mechanisms of reactionsMicro- and nanosystemsHaematological tumoursGenome structure and regulationGene expression (incl. microarray and other genome-wide approaches)
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Publications (8)

|Jul 03, 2026
Structural basis of the regulation by CDK11 kinase of early spliceosome activation and evidence for its proofreading by DHX15 helicase.

|May 22, 2024
Structural insights into the cross-exon to cross-intron spliceosome switch.

Zhenwei Zhang, Vinay Kumar, Olexandr Dybkov

|Apr 11, 2024
PRPF8-mediated dysregulation of hBrr2 helicase disrupts human spliceosome kinetics and 5´-splice-site selection causing tissue-specific defects.

Robert Atkinson, Maria Georgiou, Chunbo Yang

|Feb 22, 2024
Cryo-EM analyses of dimerized spliceosomes provide new insights into the functions of B complex proteins.

Zhenwei Zhang, Vinay Kumar, Olexandr Dybkov

|Mar 03, 2023
Regulation of 3' splice site selection after step 1 of splicing by spliceosomal C* proteins.

Olexandr Dybkov, Marco Preußner, Leyla El Ayoubi

|Aug 05, 2021
Structural insights into how Prp5 proofreads the pre-mRNA branch site.

Zhenwei Zhang, Norbert Rigo, Olexandr Dybkov

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Frequent Collaborators

5 joint publications

Olexandr Dybkov

5 joint publications

Henning Urlaub

4 joint publications

Holger Stark

4 joint publications

Vinay Kumar