Marc-David Ruepp

13PUBLICATIONS
90CO-AUTHORS
Neurology and neuromuscular diseasesLiquid biopsiesHypersonic propulsion and hypersonic aerothermodynamicsGenome structure and regulationMolecular targets
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Publications (13)

|Jun 25, 2026
Karyoptosis mediates cell death and neurodegeneration upon proteotoxic stress.

|Feb 27, 2026
Breaking β-sheets in FUS prion-like domain preserves phase separation and function but prevents aggregation and toxicity.

Noah Wake, Juan Alcalde, Daniel Jutzi

|Dec 15, 2025
U7 small nuclear RNA splice-switching therapeutics for STMN2 and UNC13A in Amyotrophic Lateral Sclerosis.

Puja R Mehta, Tomas Solomon, Sarah Pickles

|Aug 22, 2025
An alternative cytoplasmic SFPQ isoform with reduced phase separation potential is up-regulated in ALS.

Jacob Neeves, Marija Petrić Howe, Oliver J Ziff

|May 19, 2025
Single-cell RNA-sequencing reveals early mitochondrial dysfunction unique to motor neurons shared across FUS- and TARDBP-ALS.

Christoph Schweingruber, Jik Nijssen, Jonas Mechtersheimer

|Dec 19, 2023
G-quadruplexes control hepatitis B virus replication by promoting cccDNA transcription and phase separation in hepatocytes.

Guillaume Giraud, Mélanie Rodà, Pélagie Huchon

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Frequent Collaborators

5 joint publications

Daniel Jutzi

3 joint publications

Christoph Schweingruber

2 joint publications

Oliver Mühlemann

2 joint publications

Adrian M Isaacs