John P C Le Quesne

22PUBLICATIONS

203CO-AUTHORS

Predictive and prognostic markersHaematological tumoursMolecular targetsLiquid biopsiesImage processing

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Publications (22)

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|Jun 15, 2026

Integrated stress response couples mitochondrial fitness with lineage reprogramming to drive cancer evolution.

|Apr 29, 2026

Evolutionary characterization of lung cancer metastasis.

|Mar 04, 2026

Vγ1 γδ T cells steer airway macrophages toward a profibrotic response in an autochthonous lung cancer mouse model.

Ximena L Raffo-Iraolagoitia, Amanda J McFarlane, Sarah Laing

|Dec 18, 2025

Nucleophosmin supports WNT-driven hyperproliferation and tumor initiation.

Georgios Kanellos, Chiara Giacomelli, Alexander Raven

|Dec 13, 2025

Inhibiting translation elongation by reducing eIF5A activity induces feedback inhibition of initiation, limiting tumour cell proliferation.

Aristeidis P Sfakianos, Rebecca M Raven, Tom Smith

|Dec 10, 2025

Somatic evolution following cancer treatment in normal tissue.

Oriol Pich, Sophia Ward, Andrew Rowan

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Frequent Collaborators

David Moore

Leah Officer-Jones

Charles Swanton

Mariam Jamal-Hanjani

Colin Nixon

Nicholas McGranahan

Takahiro Karasaki

Crispin Miller

Daniel Murphy

Sophia Ward

Frequent Collaborators

David Moore

Leah Officer-Jones

Charles Swanton

Mariam Jamal-Hanjani