David R Edgell

16PUBLICATIONS
22CO-AUTHORS
Molecular evolutionWater treatment processesBiologically active moleculesMedical devicesBiomaterials
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Publications (16)

|Jul 29, 2026
The activity, divergence, and evolutionary degradation of modern-day homing endonucleases and their reconstructed ancestors.

|Apr 14, 2026
PHYCUT: Scalable Multiplex CRISPR/Cas9 Editing for Genome Engineering in the Diatom Phaeodactylum tricornutum.

Emily E Stuckless, Lian S Gai, Samuel S Slattery

|Jan 15, 2026
Machine learning reveals sequence and methylation determinants of SaCas9-PAM interactions in bacteria.

Dalton T Ham, Tyler S Browne, Claire Q Zhang

|Jan 07, 2026
Modular determinants of cleavage preference in GIY-YIG nucleases revealed by block-based DNA shuffling and directed evolution.

Kurt W Loedige, Mairwyn A Hall, Sabin Ghimirey

|Sep 07, 2025
Genetic Entanglement Enables Ultrastable Biocontainment in the Mammalian Gut.

Gary W Foo, Aathavan S Uruthirapathy, Claire Q Zhang

|May 15, 2025
Ku limits RNA-induced innate immunity to allow Alu expansion in primates.

Yimeng Zhu, Angelina Li, Suvrajit Maji

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Frequent Collaborators

4 joint publications

Bogumil J Karas

3 joint publications

Gregory B Gloor

2 joint publications

Tyler S Browne

2 joint publications

Gary W Foo