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Joseph J Castillo

5PUBLICATIONS
16CO-AUTHORS
Industrial molecular engineering of nucleic acids and proteinsElectrochemical energy storage and conversionAutoimmunity
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Journal

Publications (5)

Sort by Publication Date:
|May 20, 2026
Human islet amyloid polypeptide aggregation upregulates the mitochondrial cholesterol transport protein StAR and induces mitochondrial dysfunction in beta cells.

|Feb 10, 2025
Increased Steroidogenic Acute Regulatory Protein Contributes to Cholesterol-induced β-Cell Dysfunction.

Rehana Akter, Meghan F Hogan, Nathalie Esser

|Sep 08, 2024
The islet tissue plasminogen activator/plasmin system is upregulated with human islet amyloid polypeptide aggregation and protects beta cells from aggregation-induced toxicity.

Nathalie Esser, Meghan F Hogan, Andrew T Templin

|Jul 24, 2022
Islet amyloid polypeptide aggregation exerts cytotoxic and proinflammatory effects on the islet vasculature in mice.

Joseph J Castillo, Alfred C Aplin, Daryl J Hackney

|Jul 31, 2020
Low concentration IL-1β promotes islet amyloid formation by increasing hIAPP release from humanised mouse islets in vitro.

Andrew T Templin, Mahnaz Mellati, Daniel T Meier

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Frequent Collaborators

5 joint publications

Andrew T Templin

5 joint publications

Meghan F Hogan

5 joint publications

Sakeneh Zraika

5 joint publications

Rebecca L Hull-Meichle

5 joint publications

Steven E Kahn

4 joint publications

Nathalie Esser

3 joint publications

Rehana Akter

3 joint publications

Daniel P Raleigh

2 joint publications

Daniel T Meier

2 joint publications

Alfred C Aplin

Frequent Collaborators

5 joint publications

Andrew T Templin

5 joint publications

Meghan F Hogan

5 joint publications

Sakeneh Zraika

5 joint publications

Rebecca L Hull-Meichle