Saeed Izadi

7PUBLICATIONS
22CO-AUTHORS
Computational physiologyApplied immunology (incl. antibody engineering, xenotransplantation and t-cell therapies)
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Publications (7)

|Aug 13, 2026
Local electrostatics governs tryptophan oxidation and enables rational stability engineering in antibodies.

|Jul 31, 2026
Self-interaction nanoparticle spectroscopy predicts high-concentration viscosity of therapeutic IgG1 antibodies.

|Mar 24, 2026
Fab-Fc and Fab-Fab interactions of variable strength and valency contribute to the high concentration viscosity of IgG1 antibodies.

Joel Heisler, Jennifer L Hofmann, Zhenyu Tan

|Jul 19, 2024
Modulation of the high concentration viscosity of IgG1 antibodies using clinically validated Fc mutations.

Joel Heisler, Daniel Kovner, Saeed Izadi

|Jan 25, 2024
Variable domain mutational analysis to probe the molecular mechanisms of high viscosity of an IgG1 antibody.

Jing Dai, Saeed Izadi, Jonathan Zarzar

|Mar 08, 2021
Fc galactosylation follows consecutive reaction kinetics and enhances immunoglobulin G hexamerization for complement activation.

Bingchuan Wei, Xuan Gao, Lance Cadang

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Frequent Collaborators

4 joint publications

Paul J Carter

2 joint publications

Joel Heisler

1 joint publications

Cholpon Tilegenova

1 joint publications

Jianping Yin