Bruno Canard

7PUBLICATIONS
21CO-AUTHORS
Molecular targetsMedical molecular engineering of nucleic acids and proteinsNanoelectromechanical systemsGenome structure and regulation
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Publications (7)

|Jun 09, 2026
Consecutive catalytic steps of viral RNA polymerase and exonuclease suggest a way to overcome intrinsic nucleotide analogue resistance.

|Dec 14, 2023
An exonuclease-resistant chain-terminating nucleotide analogue targeting the SARS-CoV-2 replicase complex.

Ashleigh Shannon, Aurélie Chazot, Mikael Feracci

|Nov 28, 2023
Internal RNA 2'-O-methylation on the HIV-1 genome impairs reverse transcription.

Alice Decombe, Olve Peersen, Priscila Sutto-Ortiz

|Oct 20, 2022
A second type of N7-guanine RNA cap methyltransferase in an unusual locus of a large RNA virus genome.

Ashleigh Shannon, Bhawna Sama, Pierre Gauffre

|Feb 03, 2022
A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase.

Ashleigh Shannon, Véronique Fattorini, Bhawna Sama

|Sep 18, 2020
Rapid incorporation of Favipiravir by the fast and permissive viral RNA polymerase complex results in SARS-CoV-2 lethal mutagenesis.

Ashleigh Shannon, Barbara Selisko, Nhung-Thi-Tuyet Le

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