Tilman Borggrefe

16PUBLICATIONS
62CO-AUTHORS
Biologically active moleculesMolecular targetsGenome structure and regulationMedical biochemistry - amino acids and metabolitesGene expression (incl. microarray and other genome-wide approaches)
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Publications (16)

|Jul 02, 2026
Small molecule-mediated activation of Notch signal transduction.

|Jul 10, 2025
A noncoding mutation in the NOTCH1 gene initiates oncogenic NOTCH signaling via wild-type NICD stabilization in CLL.

Min Guo, Tugba Memis, Alena Sophie Ehrmann

|Jun 02, 2025
NOTCH1 signaling is dysregulated by loss of the deubiquitinase USP28 with del(11q), uncovering USP28 inhibition as novel therapeutic target in CLL.

Alena Sophie Ehrmann, Miguel Quijada-Álamo, Viola Close

|Feb 01, 2025
Effective in vivo binding energy landscape illustrates kinetic stability of RBPJ-DNA binding.

Duyen Huynh, Philipp Hoffmeister, Tobias Friedrich

|Dec 16, 2024
Lysine and arginine methylation of transcription factors.

Benedetto Daniele Giaimo, Francesca Ferrante, Tilman Borggrefe

|Apr 22, 2024
Comprehensive genomic features indicative for Notch responsiveness.

Benedetto Daniele Giaimo, Tobias Friedrich, Francesca Ferrante

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Frequent Collaborators

7 joint publications

Benedetto Daniele Giaimo

5 joint publications

Franz Oswald

5 joint publications

Tobias Friedrich

4 joint publications

Marek Bartkuhn