Tyler C Detomasi

8PUBLICATIONS
58CO-AUTHORS
Molecular targetsCheminformatics and quantitative structure-activity relationshipsProteomics and intermolecular interactions (excl. medical proteomics)Image processingPlant pathology
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (8)

|Jun 01, 2026
A Prodrug Strategy to Conditionally Trap Therapeutic Payloads for Improved Tumor Retention.

|Jan 06, 2026
Discovery of Coronavirus Main Protease Inhibitors with Enhanced Brain Exposure and Potent Oral Efficacy in SARS-CoV-2 and MERS Infection Models.

Luca Lizzadro, Jiapeng Li, Taha Y Taha

|Apr 23, 2025
Structure-based discovery of highly bioavailable, covalent, broad-spectrum coronavirus MPro inhibitors with potent in vivo efficacy.

Tyler C Detomasi, Gilles Degotte, Sijie Huang

|Mar 27, 2025
Leucine aminopeptidase LyLAP enables lysosomal degradation of membrane proteins.

Aakriti Jain, Isaac Heremans, Gilles Rademaker

|Jul 28, 2023
A Prototype Assay Multiplexing SARS-CoV-2 3CL-Protease and Angiotensin-Converting Enzyme 2 for Saliva-Based Diagnostics in COVID-19.

Vallabh Suresh, Daniel A Sheik, Tyler C Detomasi

|Feb 15, 2023
Characterization of a unique polysaccharide monooxygenase from the plant pathogen Magnaporthe oryzae.

Alejandra Martinez-D'Alto, Xia Yan, Tyler C Detomasi

Pageof 2

Frequent Collaborators

4 joint publications

Charles S Craik

2 joint publications

Eric R Hantz

2 joint publications

Nevan J Krogan

2 joint publications

Richard I Sayler