Sara J Buhrlage

17PUBLICATIONS
91CO-AUTHORS
Immunogenetics (incl. genetic immunology)Molecular targetsProteins and peptidesHaematological tumoursContaminant hydrology
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Publications (17)

|Sep 15, 2026
Discovery of JH-XIII-05-01, a First-in-Class Dual IRAK1/IRAK4 Degrader for MYD88 Mutant Lymphomas.

|Mar 19, 2026
Inhibition of USP7 Destabilizes the Noncanonical PRC1.1 Complex and Induces Neuroblastoma Differentiation.

Emily A Cmarik, Abhishek Wahi, Sayali S Chandekar

|Jan 20, 2026
Structure-Guided Design of Potent and Selective Covalent Inhibitors Targeting the SARS-CoV-2 Papain-like Protease.

Mona Sharafi, Wei Pin Teh, Jeremy Green

|Jan 03, 2026
Discovery and Characterization of a First-In-Class HCK/BTK PROTAC DFCI-002-06 for the Treatment of MYD88 Mutated B Cell Malignancies.

John M Hatcher, Shirong Liu, Amanda Kofides

|Oct 14, 2025
Small-molecule allosteric activator of ubiquitin-specific protease 7 (USP7).

Isabella Jaen Maisonet, Mona Sharafi, Emilie J Korchak

|Sep 22, 2025
Functional spectrum of USP7 pathogenic variants in Hao-Fountain syndrome: Insights into the enzyme's activity, stability, and allosteric modulation.

Emilie J Korchak, Mona Sharafi, Isabella Jaen Maisonet

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Frequent Collaborators

5 joint publications

Jarrod A Marto

4 joint publications

Isabella Jaen Maisonet

3 joint publications

Wai Cheung Chan

3 joint publications

Irina Bezsonova