Sara J Buhrlage

16PUBLICATIONS
91CO-AUTHORS
Molecular targetsProteins and peptidesHaematological tumoursContaminant hydrologyHydrology not elsewhere classified
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (16)

|Mar 19, 2026
Inhibition of USP7 Destabilizes the Noncanonical PRC1.1 Complex and Induces Neuroblastoma Differentiation.

Emily A Cmarik, Abhishek Wahi, Sayali S Chandekar

|Jan 20, 2026
Structure-Guided Design of Potent and Selective Covalent Inhibitors Targeting the SARS-CoV-2 Papain-like Protease.

Mona Sharafi, Wei Pin Teh, Jeremy Green

|Jan 03, 2026
Discovery and Characterization of a First-In-Class HCK/BTK PROTAC DFCI-002-06 for the Treatment of MYD88 Mutated B Cell Malignancies.

John M Hatcher, Shirong Liu, Amanda Kofides

|Oct 14, 2025
Small-molecule allosteric activator of ubiquitin-specific protease 7 (USP7).

Isabella Jaen Maisonet, Mona Sharafi, Emilie J Korchak

|Sep 22, 2025
Functional spectrum of USP7 pathogenic variants in Hao-Fountain syndrome: Insights into the enzyme's activity, stability, and allosteric modulation.

Emilie J Korchak, Mona Sharafi, Isabella Jaen Maisonet

Pageof 3