Brian G Lawhorn

7PUBLICATIONS
6CO-AUTHORS
Molecular targetsOrganometallic chemistryBiomolecular modelling and designCheminformatics and quantitative structure-activity relationships
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Publications (7)

|Mar 16, 2021
TRPV4 antagonists: a patent review (2015-2020).

Brian G Lawhorn, Edward J Brnardic, David J Behm

|Feb 08, 2021
Diastereoselective Copper-Mediated Conjugate Addition of Functionalized Magnesiates for the Preparation of Bisaryl Nrf2 Activators.

Michal P Glogowski, Jay M Matthews, Brian G Lawhorn

|Nov 17, 2020
Design and Optimization of an Acyclic Amine Series of TRPV4 Antagonists by Electronic Modulation of Hydrogen Bond Interactions.

Jaclyn R Patterson, Lamont R Terrell, Carla A Donatelli

|Sep 19, 2019
Discovery of GSK3527497: A Candidate for the Inhibition of Transient Receptor Potential Vanilloid-4 (TRPV4).

Carl A Brooks, Linda S Barton, David J Behm

|Dec 01, 2018
Design and Optimization of Sulfone Pyrrolidine Sulfonamide Antagonists of Transient Receptor Potential Vanilloid-4 with in Vivo Activity in a Pulmonary Edema Model.

Joseph E Pero, Jay M Matthews, David J Behm

|Oct 19, 2018
Discovery of Pyrrolidine Sulfonamides as Selective and Orally Bioavailable Antagonists of Transient Receptor Potential Vanilloid-4 (TRPV4).

Edward J Brnardic, Guosen Ye, Carl Brooks

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Frequent Collaborators

4 joint publications

Edward J Brnardic

2 joint publications

Joseph E Pero

1 joint publications

Carl A Brooks

1 joint publications

Jaclyn R Patterson