Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Tika R Malla

5PUBLICATIONS
40CO-AUTHORS
Proteins and peptidesBiologically active moleculesCheminformatics and quantitative structure-activity relationshipsBiomolecular modelling and design
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Featured researcher

Get your video featured.

JoVEPublish with JoVE
Journal

Publications (5)

Sort by Publication Date:
|May 22, 2023
In vitro selection of macrocyclic peptide inhibitors containing cyclic γ<sup>2,4</sup>-amino acids targeting the SARS-CoV-2 main protease.

Takashi Miura, Tika R Malla, C David Owen

|Feb 09, 2023
Alkyne Derivatives of SARS-CoV-2 Main Protease Inhibitors Including Nirmatrelvir Inhibit by Reacting Covalently with the Nucleophilic Cysteine.

Lennart Brewitz, Leo Dumjahn, Yilin Zhao

|Dec 01, 2021
Structure-Activity Studies Reveal Scope for Optimisation of Ebselen-Type Inhibition of SARS-CoV-2 Main Protease.

Siegfried T D Thun-Hohenstein, Timothy F Suits, Tika R Malla

|Nov 11, 2021
Discovery of SARS-CoV-2 M<sup>pro</sup> peptide inhibitors from modelling substrate and ligand binding.

H T Henry Chan, Marc A Moesser, Rebecca K Walters

|Jan 19, 2021
Mass spectrometry reveals potential of β-lactams as SARS-CoV-2 M<sup>pro</sup> inhibitors.

Tika R Malla, Anthony Tumber, Tobias John

Pageof 1

Frequent Collaborators

5 joint publications

Christopher J Schofield

4 joint publications

Lennart Brewitz

4 joint publications

Martin A Walsh

3 joint publications

C David Owen

2 joint publications

Tobias John

2 joint publications

Claire Strain-Damerell

2 joint publications

Petra Lukacik

2 joint publications

H T Henry Chan

2 joint publications

Fernanda Duarte

1 joint publications

Pratheesh Maheswaran

Frequent Collaborators

5 joint publications

Christopher J Schofield

4 joint publications

Lennart Brewitz

4 joint publications

Martin A Walsh

3 joint publications

C David Owen

Top Related Videos

A Fluorogenic Peptide Cleavage Assay to Screen for Proteolytic Activity: Applications for coronavirus spike protein activation
07:53

A Fluorogenic Peptide Cleavage Assay to Screen for Proteolytic Activity: Applications for coronavirus spike protein activation

Published on : Jan 09, 2019

33.3K
Engineering Antiviral Agents <em>via</em> Surface Plasmon Resonance
13:00

Engineering Antiviral Agents <em>via</em> Surface Plasmon Resonance

Published on : Jun 14, 2022

2.4K
Overexpressing and Purifying a Toxic Nuclease from <em>Escherichia coli</em>
08:13

Overexpressing and Purifying a Toxic Nuclease from <em>Escherichia coli</em>

Published on : Aug 29, 2025

188
See more related videos

Top Related Videos

A Fluorogenic Peptide Cleavage Assay to Screen for Proteolytic Activity: Applications for coronavirus spike protein activation
07:53

A Fluorogenic Peptide Cleavage Assay to Screen for Proteolytic Activity: Applications for coronavirus spike protein activation

Published on : Jan 09, 2019

33.3K
Engineering Antiviral Agents <em>via</em> Surface Plasmon Resonance
13:00

Engineering Antiviral Agents <em>via</em> Surface Plasmon Resonance

Published on : Jun 14, 2022

2.4K
Overexpressing and Purifying a Toxic Nuclease from <em>Escherichia coli</em>
08:13

Overexpressing and Purifying a Toxic Nuclease from <em>Escherichia coli</em>

Published on : Aug 29, 2025

188
See more related videos