Nicholas D Lakin

8PUBLICATIONS
20CO-AUTHORS
Molecular targetsNonlinear optics and spectroscopyMedical infection agents (incl. prions)Preventative health careRadiation therapy
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Publications (8)

|Jul 03, 2026
G-quadruplex homeostasis is a determinant of PARP inhibitor toxicity in BRCA2-deficient cells.

|Jun 03, 2024
The loss of DNA polymerase epsilon accessory subunits POLE3-POLE4 leads to BRCA1-independent PARP inhibitor sensitivity.

Hasan Mamar, Roberta Fajka-Boja, Mónika Mórocz

|Aug 17, 2023
C16orf72/HAPSTR1/TAPR1 functions with BRCA1/Senataxin to modulate replication-associated R-loops and confer resistance to PARP disruption.

Abhishek Bharadwaj Sharma, Muhammad Khairul Ramlee, Joel Kosmin

|Jul 18, 2023
Regulation of Rad52-dependent replication fork recovery through serine ADP-ribosylation of PolD3.

Frederick Richards, Marta J Llorca-Cardenosa, Jamie Langton

|Jan 14, 2022
Linking DNA repair and cell cycle progression through serine ADP-ribosylation of histones.

Julien Brustel, Tetsuya Muramoto, Kazuki Fumimoto

|Feb 23, 2018
PARP1 and PARP2 stabilise replication forks at base excision repair intermediates through Fbh1-dependent Rad51 regulation.

George E Ronson, Ann Liza Piberger, Martin R Higgs

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Frequent Collaborators

5 joint publications

Abhishek Bharadwaj Sharma

2 joint publications

Martin R Higgs

2 joint publications

George E Ronson

2 joint publications

Daniel Ebner