Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Bruce Ruggeri

2PUBLICATIONS

50CO-AUTHORS

Molecular targets

Featured researcher

Get your video featured.

Publish with JoVE

Featured researcher

Get your video featured.

Publish with JoVE

Publications (2)

Sort by Publication Date:

|Sep 24, 2025

PRT3789 Is a First-in-Human SMARCA2-Selective Degrader That Induces Synthetic Lethality in SMARCA4-Mutated Cancers.

Michael Hulse, Min Wang, Chaoyi Xu

|Oct 20, 2023

PRMT5 Inhibitors Regulate DNA Damage Repair Pathways in Cancer Cells and Improve Response to PARP Inhibition and Chemotherapies.

Jack Carter, Michael Hulse, Monisha Sivakumar

Pageof 1

Frequent Collaborators

2 joint publications

Jack Carter

2 joint publications

Monisha Sivakumar

2 joint publications

Jessica Burtell

2 joint publications

Koichi Ito

2 joint publications

Min Wang

2 joint publications

Anjana Agarwal

2 joint publications

Komali Vykuntam

2 joint publications

Peggy Scherle

2 joint publications

Neha Bhagwat

2 joint publications

Joseph Rager

Frequent Collaborators

2 joint publications

Jack Carter

2 joint publications

Monisha Sivakumar

2 joint publications

Jessica Burtell

2 joint publications

Koichi Ito

Top Related Videos

Dual CRISPR-Interference Strategy for Targeting Synthetic Lethal Interactions Between Non-Coding RNAs in Cancer Cells

Dual CRISPR-Interference Strategy for Targeting Synthetic Lethal Interactions Between Non-Coding RNAs in Cancer Cells

Published on : May 30, 2025

Laser Microirradiation to Study <em>In Vivo</em> Cellular Responses to Simple and Complex DNA Damage

Laser Microirradiation to Study <em>In Vivo</em> Cellular Responses to Simple and Complex DNA Damage

Published on : Jan 31, 2018

See more related videos

Top Related Videos

Dual CRISPR-Interference Strategy for Targeting Synthetic Lethal Interactions Between Non-Coding RNAs in Cancer Cells

Dual CRISPR-Interference Strategy for Targeting Synthetic Lethal Interactions Between Non-Coding RNAs in Cancer Cells

Published on : May 30, 2025

Laser Microirradiation to Study <em>In Vivo</em> Cellular Responses to Simple and Complex DNA Damage

Laser Microirradiation to Study <em>In Vivo</em> Cellular Responses to Simple and Complex DNA Damage

Published on : Jan 31, 2018

See more related videos