Xiaohong Sang

8PUBLICATIONS
15CO-AUTHORS
Cheminformatics and quantitative structure-activity relationshipsProteins and peptidesCharacterisation of biological macromoleculesMedical virologyNeurology and neuromuscular diseases
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Publications (8)

|Nov 14, 2025
Structure-guided discovery of a small molecule inhibitor of SARS-CoV-2 main protease with potent in vitro and in vivo antiviral activities.

Shuofeng Yuan, Juan Wang, Xiaohong Sang

|Sep 15, 2025
Discovery of a potent covalent inhibitor that unusually distorts the catalytic dyad of SARS-CoV-2 main protease.

Juan Wang, Xiaohong Sang, Wenyan Zheng

|Jul 17, 2025
The cryo-EM-delineated mechanism underlying mimicry of CXCR4 agonism enables widespread stem cell neuroprotection in a mouse model of ALS.

Xiaohong Sang, Haizhan Jiao, Qian Meng

|May 19, 2025
Computational and Experimental Study of the Conformational Variation of the Catalytic Residue His41 of the SARS-CoV-2 Main Protease.

Jiao Zhou, Xiang Liu, Yan Xu

|Mar 10, 2025
Structural mechanisms underlying the modulation of CXCR4 by diverse small-molecule antagonists.

Xiaohong Sang, Haizhan Jiao, Qian Meng

|Oct 16, 2024
Discovery of Novel Nonpeptidic Proteasome Inhibitors Using Covalent Virtual Screening and Biological Evaluation.

Jiao Zhou, Xiaohong Sang, Meixian Wu

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Frequent Collaborators

4 joint publications

Jiao Zhou

3 joint publications

Arieh Warshel

2 joint publications

Arjun Saha

2 joint publications

Ziwei Huang