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Dean R Kahn

4PUBLICATIONS

38CO-AUTHORS

Biomolecular modelling and designGene and molecular therapyMolecular targets

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Publications (4)

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|Feb 19, 2025

Design of Potent Menin-KMT2A Interaction Inhibitors with Improved <i>In Vitro</i> ADME Properties and Reduced hERG Affinity.

Bruno D Chapsal, Jennifer R Kimbrough, Stephanie M Bester

|Aug 01, 2024

Discovery of Pyrazolopyrazines as Selective, Potent, and Mutant-Active MET Inhibitors with Intracranial Efficacy.

Quinn A Bumpers, Robert W Pipal, Anna M Benz-Weeden

|Jul 30, 2024

Identification of the Clinical Candidate <b>PF-07284890</b> (<b>ARRY-461</b>), a Highly Potent and Brain Penetrant BRAF Inhibitor for the Treatment of Cancer.

Li Ren, David Moreno, Brian R Baer

|May 01, 2024

A Next-Generation BRAF Inhibitor Overcomes Resistance to BRAF Inhibition in Patients with BRAF-Mutant Cancers Using Pharmacokinetics-Informed Dose Escalation.

Rona Yaeger, Meredith A McKean, Rizwan Haq

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Frequent Collaborators

2 joint publications

Brian R Baer

2 joint publications

Jay B Fell

2 joint publications

Erik J Hicken

1 joint publications

Quinn A Bumpers

1 joint publications

James T Brewster

1 joint publications

Mohamed S A Elsayed

1 joint publications

Ronald J Hinklin

1 joint publications

Rona Yaeger

1 joint publications

Meredith A McKean

1 joint publications

Rizwan Haq

Frequent Collaborators

2 joint publications

Brian R Baer

2 joint publications

Jay B Fell

2 joint publications

Erik J Hicken

1 joint publications

Quinn A Bumpers

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