Jacob M Hughes

4PUBLICATIONS
26CO-AUTHORS
Molecular targets
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Publications (4)

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|Sep 08, 2026
HRAS promotes mutant NRAS-driven transformation with codon and allele specificity.

|Nov 25, 2025
SOS1 inhibition suppresses the emergence of osimertinib resistance to generate a durable response in EGFR-mutant lung cancer.

Brianna R Daley, Patricia L Theard, Jacob M Hughes

|Sep 16, 2025
Wild-type RAS signaling is an essential therapeutic target in RAS-mutated cancers.

Nancy E Sealover, Bridget A Finniff, Jacob M Hughes

|Oct 22, 2024
SOS1 Inhibition Enhances the Efficacy of KRASG12C Inhibitors and Delays Resistance in Lung Adenocarcinoma.

Brianna R Daley, Nancy E Sealover, Bridget A Finniff

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Frequent Collaborators

4 joint publications

Robert L Kortum

3 joint publications

Joseph P LaMorte

3 joint publications

Matthew D Wilkerson

2 joint publications

Brianna R Daley

2 joint publications

Nancy E Sealover

2 joint publications

Bridget A Finniff

2 joint publications

Erin Sheffels

2 joint publications

Marco H Hofmann

2 joint publications

Kaja Kostyrko

2 joint publications

Amanda Linke

Frequent Collaborators

4 joint publications

Robert L Kortum

3 joint publications

Joseph P LaMorte

3 joint publications

Matthew D Wilkerson

2 joint publications

Brianna R Daley

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