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Videos de Conceptos Relacionados

Zygotic Development And Stem Cell Formation01:10

Zygotic Development And Stem Cell Formation

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The development of all multicellular organisms starts with the fusion of haploid cells called sperm and egg to form a diploid zygote. A zygote is a totipotent cell that can develop into a complete organism. The zygote undergoes cell division or cleavage to form an 8-cell mass. Until this stage, the cells are spherical, loosely attached, and remain totipotent. Totipotent cells are capable of developing both the embryonic and the extraembryonic tissues. However, as they continue to divide, they...
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Gastrulation01:56

Gastrulation

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Gastrulation establishes the three primary tissues of an embryo: the ectoderm, mesoderm, and endoderm. This developmental process relies on a series of intricate cellular movements, which in humans transforms a flat, “bilaminar disc” composed of two cell sheets into a three-tiered structure. In the resulting embryo, the endoderm serves as the bottom layer, and stacked directly above it is the intermediate mesoderm, and then the uppermost ectoderm. Respectively, these tissue strata...
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Whole Body Regeneration01:33

Whole Body Regeneration

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Regeneration is the process of restoring injured or lost tissues, organs, or body parts. While simpler organisms generally show greater ability to regenerate their whole body, few complex animals show similarly exceptional regeneration. For example, planarian flatworms have a unique regenerative potential making them a popular study organism among biologists to understand the mechanisms of whole body regeneration. Other organisms, such as hydra, also show extreme regeneration potential;...
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Cleavage and Blastulation01:33

Cleavage and Blastulation

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After a large-single-celled zygote is produced via fertilization, the process of cleavage occurs while zygotes travel through the uterine tube. Cleavage is a mitotic cell division that does not result in growth. With each round of successive cell division, daughter cells get increasingly smaller.
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Cellular Differentiation00:57

Cellular Differentiation

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How does a complex organism such as a human develop from a single cell? It all starts from a single fertilized egg which gives rise to a vast array of cell types, such as nerve cells, muscle cells, and epithelial cells that characterize the adult? Throughout development and adulthood, cellular differentiation leads cells to assume their final morphology and physiology. Differentiation is the process by which unspecialized cells become specialized to carry out distinct functions.
A zygote is a...
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Convergent Evolution01:54

Convergent Evolution

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Evolution shapes the features of organisms over time, ensuring that they are suited for the environments in which they live. Sometimes, selection pressure leads to the rise of similar but unrelated adaptations in organisms with no recent common ancestors, a process known as convergent evolution.
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Video Experimental Relacionado

Updated: Jun 8, 2025

The Power of Simplicity: Sea Urchin Embryos as in Vivo Developmental Models for Studying Complex Cell-to-cell Signaling Network Interactions
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The Power of Simplicity: Sea Urchin Embryos as in Vivo Developmental Models for Studying Complex Cell-to-cell Signaling Network Interactions

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Un programa de desarrollo multicelular en un pariente animal cercano

Marine Olivetta1,2, Chandni Bhickta1, Nicolas Chiaruttini3

  • 1Swiss Institute for Experimental Cancer Research, School of Life Sciences, Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland.

Nature
|November 7, 2024
PubMed
Resumen

El desarrollo multicelular, esencial para los animales, puede haberse originado antes de lo que se pensaba. La investigación sobre Chromosphaera perkinsii revela un desarrollo temprano similar al animal en un pariente cercano, lo que sugiere orígenes antiguos o evolución convergente de este rasgo.

Área de la Ciencia:

  • Biología del desarrollo evolutivo
  • Biología celular y molecular
  • Protistología

Sus antecedentes:

  • Los animales se desarrollan a partir de cigotos unicelulares a través de la embriogénesis conservada.
  • El origen evolutivo de la multicelularidad animal sigue siendo en gran medida desconocido.

Objetivo del estudio:

  • Para investigar el programa de desarrollo de Chromosphaera perkinsii, un pariente de divergencia temprana de los animales.
  • Para obtener información sobre los orígenes evolutivos del desarrollo multicelular de los animales.

Principales métodos:

  • Imagen con resolución de tiempo del desarrollo de C. perkinsii.
  • Perfiles transcriptómicos para analizar la expresión génica durante el desarrollo.

Principales resultados:

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Embryo Microinjection and Electroporation in the Chordate Ciona intestinalis
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  • C. perkinsii exhibe ruptura de simetría y divisiones de escisión desde una sola célula.
  • Este proceso da como resultado una colonia multicelular con tipos celulares distintos.
  • El programa de desarrollo es autónomo y palintómico.

Conclusiones:

  • El desarrollo multicelular en C. perkinsii sugiere que es mucho más antiguo de lo que se suponía anteriormente o evolucionó convergentemente en ictiosporeas.
  • Proporciona un modelo para comprender la evolución temprana del desarrollo animal.