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Updated: Oct 19, 2026

A 3D Digital Model for the Diagnosis and Treatment of Pulmonary Nodules
Published on: May 19, 2023
Pulmonary nodule mimicking lung cancer in a human immunodeficiency virus type-1 infected patient
T Takahashi1, T Endou, T Nakamura
1Department of Infectious Diseases, Institute of Medical Science, University of Tokyo, Japan. takahata@ims.u-tokyo.ac.jp
Insights
Human immunodeficiency virus type 1 (HIV-1) patients can develop pulmonary nodules that mimic cancer. Antituberculosis therapy successfully treated a case, highlighting the importance of CT scans for diagnosis and monitoring.
Area of Science:
- Pulmonology
- Infectious Diseases
- Radiology
Background:
- Human immunodeficiency virus type 1 (HIV-1) infection can lead to various pulmonary complications.
- Pulmonary nodules in HIV-1 patients can present diagnostic challenges, sometimes mimicking malignancy like adenocarcinoma.
- Early and accurate diagnosis is crucial for effective management of pulmonary issues in immunocompromised individuals.
Observation:
- A case report of an HIV-1 infected patient presenting with a solitary pulmonary nodule.
- The nodule's appearance on imaging was suggestive of adenocarcinoma.
- The patient received antituberculosis therapy.
Findings:
- Successful treatment of the pulmonary nodule with antituberculosis therapy.
- High-resolution computed tomography (CT) scans were instrumental in identifying inflammatory findings.
- CT scans revealed bronchial ectasis and calcifications within the nodule.
Implications:
- High-resolution CT scans are vital for detecting pulmonary inflammatory conditions in HIV-1 patients.
- CT imaging aids in differentiating inflammatory nodules from neoplastic lesions.
- Monitoring treatment effectiveness for pulmonary inflammatory nodules in HIV-1 patients is facilitated by CT scans.
Abstract:
We reported a human immunodeficiency virus type 1-infected patient with a small solitary pulmonary nodule mimicking adenocarcinoma, who was treated successfully with antituberculosis therapy. We believe that high-resolution CT scans of thorax are important examinations to detect pulmonary inflammatory findings, such as ectasis of the bronchi leading to the nodules and calcifications in the nodules, and also as follow-up tests for evaluating effectiveness of treatment on pulmonary inflammatory nodules in human immunodeficiency virus type 1-infected patients.
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