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Assessing Cortical Cerebral Microinfarcts on High Resolution MR Images
Published on: November 20, 2015
[Use of fluid-attenuated inversion recovery (FLAIR) images in brain check-up]
Y Ikeda1, K Matsumoto, T Hayashi
1Department of Neurosurgery, Showa University School of Medicine, Tokyo, Japan.
Insights
Fluid-attenuated inversion recovery (FLAIR) magnetic resonance imaging is highly sensitive for detecting brain lesions during check-ups. FLAIR excels at visualizing subtle cortical and subcortical abnormalities, improving diagnostic accuracy.
Area of Science:
- Radiology
- Neuroimaging
- Medical Imaging Techniques
Context:
- Brain check-ups require sensitive imaging methods for early lesion detection.
- Conventional T2-weighted MRI can have limitations in visualizing certain brain pathologies.
- Fluid-attenuated inversion recovery (FLAIR) is an advanced MRI sequence.
Purpose:
- To evaluate the diagnostic utility of FLAIR magnetic resonance (MR) imaging in routine brain check-ups.
- To assess FLAIR's effectiveness in detecting various brain lesions and abnormalities.
- To compare FLAIR imaging with conventional T2-weighted images for brain examination.
Summary:
- FLAIR MR imaging demonstrated high sensitivity in detecting cortical and subcortical brain lesions, particularly those near the brain surface.
- The study found FLAIR useful for evaluating periventricular hyperintensity (PVH), noting increased prevalence and severity with aging.
- FLAIR imaging aided in the differential diagnosis of lacunae and perivascular spaces, enhancing diagnostic capabilities.
Impact:
- FLAIR imaging significantly improves the detection of subtle brain lesions, crucial for early diagnosis and management.
- Findings highlight FLAIR's value in assessing age-related changes like PVH.
- This technique enhances the diagnostic accuracy of brain check-ups, potentially leading to earlier intervention for neurological conditions.
Abstract:
Fluid-attenuated inversion recovery (FLAIR) images are magnetic resonance (MR) images obtained with an inversion recovery sequence having a long inversion time (T 1) and a long echo time (TE). The purpose of this study was to evaluate the utility of FLAIR images in brain check-up. 320 healthy adults (229 males, 91 females) were examined with FLAIR sequences of several types having repetitive time (TR) of 7000 msec, inversion times of 1700 msec and echo times (TE) of 110 msec. All studies were performed on a SHIMAZU MAGNEX 100 HP 1.0 T imaging system. FLAIR images were useful in detecting cortical and subcortical lesions near the brain surface, which were unclear in the conventional T 2 weighted images. FLAIR images were useful in evaluation of periventricular hyperintensity area (PVH). Frequency and degree of PVH were increased in aging. FLAIR images were useful in the differential diagnosis of lacuna and perivascular space. In conclusion, FLAIR images were very sensitive for the detection of brain lesions in brain check-up.
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