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FIMM, a database of functional molecular immunology
C Schönbach1, J L Koh, X Sheng
1BIC/KRDL, Kent Ridge Digital Labs, 21 Heng Mui Keng Terrace, 119613 Singapore.
Insights
The FIMM database offers comprehensive data on functional molecular immunology, specifically cellular immunology. It provides detailed information on antigens, MHC molecules, peptides, and disease links, accessible via search tools.
Area of Science:
- Immunology
- Molecular Biology
- Bioinformatics
Background:
- Functional molecular immunology research requires integrated data on cellular interactions.
- Existing databases may lack comprehensive coverage of protein antigens, MHC molecules, and associated peptides.
- Understanding disease associations with immunological components is crucial.
Purpose of the Study:
- To introduce the FIMM database as a resource for functional molecular immunology.
- To consolidate referenced data on key immunological components and their disease relevance.
- To provide accessible search tools for immunological data retrieval.
Main Methods:
- Development and curation of the FIMM database.
- Inclusion of fully referenced data on protein antigens, MHC molecules, and peptides.
- Implementation of search functionalities for data extraction.
Main Results:
- The FIMM database provides a centralized repository of functional molecular immunology data.
- Data includes protein antigens, major histocompatibility complex (MHC) molecules, MHC-associated peptides, and disease associations.
- Search tools enable efficient information retrieval, presented as lists or reports.
Conclusions:
- The FIMM database serves as a valuable resource for researchers in cellular immunology.
- It facilitates the study of molecular mechanisms underlying immune responses and diseases.
- Accessible data and search tools enhance immunological research efficiency.
Abstract:
FIMM database (http://sdmc.krdl.org.sg:8080/fimm ) contains data relevant to functional molecular immunology, focusing on cellular immunology. It contains fully referenced data on protein antigens, major histocompatibility complex (MHC) molecules, MHC-associated peptides and relevant disease associations. FIMM has a set of search tools for extraction of information and results are presented as lists or as reports.