Related Experiment Video
Updated: Aug 24, 2026

High-frequency Ultrasound Imaging of Mouse Cervical Lymph Nodes
Published on: July 25, 2015
[CT-guided needle biopsy in malignant lymphoma: current techniques and its usefulness]
1Department of Radiology, Fukuyama National Hospital.
Insights
Computed tomography (CT)-guided core-needle biopsy is a highly accurate first-line diagnostic procedure for lymphoma. This image-guided technique provides sufficient information for diagnosis and treatment decisions in most lymphoma cases.
Area of Science:
- Oncology
- Radiology
- Pathology
Context:
- Accurate histological examination of biopsy specimens is crucial for malignant lymphoma management.
- Traditional biopsy methods may not always provide adequate tissue for diagnosis.
- Advancements in imaging technology offer improved diagnostic capabilities.
Purpose:
- To evaluate the efficacy of computed tomography (CT)-guided core-needle biopsy in diagnosing lymphoma.
- To present a successful biopsy technique for lymphoma diagnosis.
- To establish image-guided needle biopsy as a primary diagnostic procedure for lymphoma.
Summary:
- Histological examination of adequate biopsy specimens is fundamental to malignant lymphoma management.
- Core-needle biopsy with computed tomography (CT) offers a superior basis for lymphoma assessment.
- Image-guided needle biopsy is recommended as the initial diagnostic procedure, except for superficial nodal sites, with reported diagnostic accuracies of 83%–87%.
Impact:
- CT-guided core-needle biopsies provide sufficient information for diagnosing and treating most lymphoma cases.
- This technique can lead to earlier and more accurate lymphoma diagnosis.
- Improved diagnostic accuracy can enhance patient management and therapeutic decision-making.
Abstract:
Histological examination of adequate biopsy specimens is fundamental to the management of patients with malignant lymphoma. Core-needle biopsy with computed tomography potentially provides a better basis for this assessment. Image-guided needle biopsy should be the first procedure performed in the diagnosis of lymphoma, except in easily accessible superficial neck, inguinal, and axillary nodal sites. Recent studies have shown a diagnostic accuracy of 83% to 87%. We describe the biopsy technique that have been successful in our personal experience. From our experience, CT-guided core-needle biopsies prove sufficient information for the diagnosis of and subsequent therapeutic decision to treat most cases of lymphoma.

