[Increase of troponin I during acute pericarditis. 69 cases at an emergency service]
P Godon1, S Guérard, E Bonnefoy
1Service de Cardiologie, Hôpital Desgenettes, Lyon. patrick.godon@wanadoo.fr
Insights
Troponin I elevation is common in acute pericarditis, often correlating with ST elevation on ECGs, suggesting minor heart muscle damage. The long-term impact of this troponin rise remains uncertain.
Area of Science:
- Cardiology
- Biomarkers
- Cardiac Electrophysiology
Context:
- Acute pericarditis is an inflammation of the pericardium.
- Troponin I (TnI) is a cardiac biomarker.
- The role of TnI in pericarditis requires further elucidation.
Purpose:
- To determine the incidence of troponin I elevation in acute pericarditis.
- To assess the clinical significance of troponin I elevation in this condition.
Summary:
- A retrospective analysis of 69 patients with acute idiopathic pericarditis was conducted.
- Troponin I elevation was detected in 49% of patients, with 22% showing significantly elevated levels (> 1.5 ng/ml).
- A significant correlation was observed between elevated troponin I levels and ST elevation on ECGs.
Impact:
- Troponin I elevation is frequently observed in acute idiopathic pericarditis.
- Elevated troponin I appears to indicate superficial myocardial damage, as suggested by its correlation with ST segment elevation.
- The prognostic implications of troponin I elevation in acute pericarditis are currently unknown.
Objective:
The purpose of this study was to determine the incidence and significance of troponin i (tni) elevation in acute pericarditis.
Patients And Methods:
We retrospectively included 69 patients with acute idiopathic pericarditis. We analyzed ECG recordings, echocardiography findings and tni level. Thirty-four patients (49%) had detectable tni (> 0.5 ng/ml), 15 (22%) had a significantly elevated level (> 1.5 ng/ml). There was a significant correlation between elevated tni level and ST elevation. All patients were well at one year.
Conclusions:
A rise in tni is frequently observed during acute idiopathic pericarditis. According to the correlation with ST segment elevation, a rise in tni is apparently indicative of superficial myocardial damage. The prognostic value remains unknown.
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