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Escherichia coli chest-wall hemorrhagic cellulitis associated with central-line placement
1Infectious Disease Division, Winthrop-University Hospital, Mineola, New York 11501, USA.
Insights
Hemorrhagic cellulitis is rare, especially in the chest wall. This case highlights a unique instance of Escherichia coli-induced chest wall infection in a patient with kidney failure and a central line.
Area of Science:
- Infectious Diseases
- Bacteriology
- Clinical Medicine
Background:
- Cellulitis is a common bacterial skin infection.
- Hemorrhagic cellulitis is an unusual presentation, typically seen in immunocompromised individuals.
- Gram-negative sepsis can rarely cause hemorrhagic cellulitis, usually affecting the lower extremities.
Observation:
- A patient with renal failure and a central venous catheter developed an unusual form of cellulitis.
- The infection presented as hemorrhagic cellulitis of the chest wall.
- Escherichia coli was identified as the causative pathogen.
Findings:
- This is the first reported case of Escherichia coli chest-wall hemorrhagic cellulitis.
- The central line was a potential source of infection in this patient with compromised immunity due to renal failure.
- The presentation deviated from the typical location (below the waist) and pathogen profile for hemorrhagic cellulitis.
Implications:
- This case expands the known clinical spectrum of hemorrhagic cellulitis.
- It underscores the importance of considering unusual presentations of gram-negative infections in patients with central lines and renal failure.
- Early recognition and appropriate antibiotic therapy are crucial for managing such rare but potentially severe infections.
Abstract:
Cellulitis is a common clinical entity. Hemorrhagic cellulitis is distinctly unusual and is most frequent in compromised hosts. In normal or near normal hosts, hemorrhagic cellulitis may rarely complicate gram-negative sepsis. Usually, hemorrhagic cellulitis occurs below the waist. The differential diagnosis includes invasive streptococcal infection, mixed aerobic and anaerobic infection, gram-negative sepsis, and gross gangrene. We present the first-known case of Escherichia coli chest-wall hemorrhagic cellulitis associated with a central line in a patient with renal failure.
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