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Non-Hodgkin's lymphoma in a patient with human immunodeficiency virus

M Mahmoudi1, D Condolucci, N Freed

  • 1Department of Internal Medicine, University of Medicine and Dentistry of New Jersey School of Osteopathic Medicine, Stratford, NJ, USA. ma0003@dnamail.com

The Journal of the American Osteopathic Association
|May 2, 2001
PubMed

Insights

This case study highlights successful treatment of diffuse, large B-cell non-Hodgkin's lymphoma in an HIV-positive patient. Effective management involved collaboration between specialists, leading to long-term remission.

Area of Science:

  • Oncology
  • Infectious Diseases
  • Gastroenterology

Background:

  • Managing concurrent human immunodeficiency virus (HIV) and cancer presents unique challenges.
  • Gastric ulcers can be a symptom of underlying malignancy in immunocompromised patients.

Observation:

  • A 38-year-old woman with HIV presented with nausea and vomiting, found to have a gastric ulcer.
  • Further investigation revealed diffuse, large B-cell non-Hodgkin's lymphoma.

Findings:

  • The patient received six cycles of chemotherapy for her lymphoma.
  • Post-treatment, endoscopy and biopsy confirmed no remaining malignancy, with the patient in remission for 23 months.

Implications:

  • This case demonstrates the feasibility of successful cancer treatment in HIV-positive individuals.
  • Emphasizes the critical role of primary care physicians in coordinating multidisciplinary care for complex cases involving HIV and malignancy.

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