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FIMM, a database of functional molecular immunology: update 2002
Christian Schönbach1, Judice L Y Koh, Darren R Flower
1BIC/KRDL, Kent Ridge Digital Labs, 21 Heng Mui Keng Terrace, 119613 Singapore.
Insights
The FIMM database offers comprehensive data on functional molecular immunology, including protein antigens, MHC molecules, and disease links. It provides search tools for easy information retrieval in cellular immunology research.
Area of Science:
- Immunology
- Molecular Biology
- Bioinformatics
Background:
- Functional molecular immunology research requires integrated data on cellular interactions.
- Databases are crucial for organizing and accessing complex immunological information.
- Understanding protein antigens and major histocompatibility complex (MHC) interactions is key to immunology.
Purpose of the Study:
- To introduce the FIMM database as a resource for functional molecular immunology.
- To highlight the database's focus on cellular immunology.
- To detail the types of data and search functionalities available.
Main Methods:
- Data compilation from referenced sources.
- Inclusion of protein antigens, MHC molecules, and associated peptides.
- Development of search tools for data extraction.
Main Results:
- The FIMM database provides comprehensive, referenced data.
- It covers protein antigens, MHC molecules, MHC-associated peptides, and disease associations.
- Search tools allow for information extraction presented as lists or reports.
Conclusions:
- The FIMM database serves as a valuable resource for researchers in functional molecular immunology.
- Its structured data and search capabilities facilitate the study of cellular immunology.
- It supports the investigation of molecular mechanisms underlying immune responses and diseases.
Abstract:
FIMM database (http://sdmc.krdl.org.sg:8080/fimm) contains data relevant to functional molecular immunology, focusing on cellular immunology. It contains fully referenced data on protein antigens, major histocompatibility complex (MHC) molecules, MHC-associated peptides and relevant disease associations. FIMM has a set of search tools for extraction of information and results are presented as lists or as reports.