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Published on: May 23, 2021
Primary lymphoma of bilateral external auditory canals
Jun Shuto1, Tomoyo Ueyama, Masashi Suzuki
1Department of Otolaryngology, University Hospital, Oita Medical University, 1-1 Idaigaoka, Hasama-machi, Oita-gun, Oita 879-5593, Japan.
Insights
This study details a rare case of B-cell lymphoma in both external auditory canals. Successful treatment involved chemotherapy and surgery, with no recurrence observed.
Area of Science:
- Oncology
- Otorhinolaryngology
- Pathology
Background:
- Primary lymphoma of the external auditory canal is exceptionally rare.
- Malignant neoplasms in this location often present with atypical symptoms.
Observation:
- A 49-year-old male presented with bilateral cauliflower-like masses in the external auditory canals.
- Initial presentation mimicked other external ear pathologies.
Findings:
- Immunohistopathology and immunoglobulin heavy chain gene rearrangement confirmed B-cell lymphoma.
- The patient had no evidence of systemic disease at diagnosis.
- This case is the third reported instance of external auditory canal lymphoma and the first with fresh tissue immunohistochemical data.
Implications:
- Highlights the importance of thorough diagnostic workup for unusual ear masses.
- Provides valuable immunohistochemical data for future diagnostic reference.
- Suggests a potential therapeutic strategy combining chemotherapy and surgical debulking for localized disease.
Abstract:
We report a rare case of primary lymphoma originating in the bilateral external auditory canals. A 49-year-old man presented with cauliflower-like tumors on both of his external auditory canals. Immunohistopathologic examination and immunoglobulin heavy chain gene rearrangement studies led to a diagnosis of B-cell lymphoma. He had no other systemic involvement. After chemotherapy, total gross tumor removal by surgery was achieved, and no recurrence has been detected during 1 year of follow-up. To our knowledge, this is the third case of malignant lymphoma originating in the external auditory canal to be reported in the literature, and this is the first report that includes immunohistochemical findings of fresh tissue.
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