Glomus tumor in the digit of a cat

Area of Science:

• Veterinary Pathology
• Oncology
• Dermatopathology

Background:

• Glomus tumors are rare neoplasms originating from glomus bodies, typically found in the skin.
• While documented in humans, their occurrence in non-human animals is exceptionally infrequent.
• This case represents a novel instance of a glomus tumor in a feline patient.

Observation:

• A 7-year-old male cross-breed cat presented with a 1.5 x 2 cm hard, white, solitary mass on the outer aspect of the third digit of the left forepaw.
• Pathological examination revealed the mass was situated in the deep dermis and subcutis.
• Histopathology showed a mixed population of epithelioid and spindle-shaped cells within a mucinous stroma, with epithelioid cells surrounding small blood vessels.

Findings:

• Immunohistochemical analysis demonstrated neoplastic cells were positive for vimentin and alpha smooth muscle actin.
• The neoplastic cells were negative for keratin, desmin, S-100 protein, and neuron-specific enolase.
• The distinct histopathological and immunohistochemical features led to the diagnosis of a glomus tumor.

Implications:

• This case report expands the known spectrum of cutaneous neoplasms in cats.
• It highlights the importance of considering rare tumor types in veterinary diagnostics.
• Further research may elucidate the specific characteristics and behavior of glomus tumors in felines.