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Primary intestinal lymphoma complicating Crohn's disease

Calvin H Hall1, Mohamad Shamma

  • 1Section of Gastroenterology, Mercy Hospital and Medical Center, Chicago, Illinois, USA. calthepro@aol.com

Journal of Clinical Gastroenterology
|March 19, 2003
PubMed

Insights

A rare case of Burkitt

Area of Science:

  • Gastroenterology
  • Oncology
  • Pathology

Background:

  • Crohn's disease is a chronic inflammatory bowel condition.
  • Lymphoma is a cancer of the lymphatic system.
  • Patients with inflammatory bowel disease have an increased risk of certain cancers.

Observation:

  • A 32-year-old male with a 12-year history of Crohn's disease presented with a cecal mass.
  • Colonoscopy revealed a 5-cm lesion in the cecum.
  • Histological examination identified high-grade B-cell lymphoma of Burkitt's type.

Findings:

  • The patient was diagnosed with Burkitt's lymphoma, a type of non-Hodgkin lymphoma.
  • Chemotherapy was administered as treatment.
  • The patient has shown positive response to treatment over 12 months.
  • Literature review identified 30 reported cases of lymphoma in Crohn's disease patients.

Implications:

  • This case highlights a rare but serious complication of long-standing Crohn's disease.
  • Early detection and diagnosis of lymphoma in IBD patients are crucial.
  • Further research may elucidate the mechanisms linking Crohn's disease and lymphoma development.

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