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Updated: Sep 20, 2026
Murine Bilateral Renal Lymphadenectomy
Published on: December 30, 2025
[Primary renal lymphoma]
J R Torrecilla García-Ripoll1, M Pascual Samaniego, S Martín Blanco
1Servicio de Urología, Servicio de Anatomía Patológica, Hospital Clínico Universitario de Valladolid, Valladolid.
Insights
This case study describes a rare instance of primary renal lymphoma, a non-Hodgkin lymphoma affecting the kidney. The patient was successfully treated with combination chemotherapy (CHOP).
Area of Science:
- Oncology
- Nephrology
- Pathology
Background:
- Primary renal lymphoma is an exceptionally rare malignancy, often challenging to diagnose due to the kidney's lack of native lymphoid tissue.
- Its clinical presentation can mimic other renal tumors, necessitating thorough diagnostic evaluation.
Observation:
- A 78-year-old male presented with right flank pain and a palpable mass.
- Imaging studies identified a renal mass, and subsequent immunohistochemical analysis confirmed a B-cell-type non-Hodgkin lymphoma.
Findings:
- Histological examination is crucial for the definitive diagnosis of primary renal lymphoma.
- The patient received combination chemotherapy using the CHOP regimen (cyclophosphamide, doxorubicin, vincristine, and prednisone).
Implications:
- This case underscores the importance of considering rare diagnoses like primary renal lymphoma in patients with renal masses.
- Chemotherapy, specifically the CHOP regimen, remains the standard and effective treatment for this condition.
- Further research may elucidate the pathogenesis and optimal management strategies for primary renal lymphoma.
Objective:
To describe a case of primary renal lymphoma.
Material And Methods:
We presents a patient with a right renal mass which histological analysis revealed a non-Hodgkin Lymphoma.
Results:
A 78-year-old male patient with right flank pain mass was referred to our Service. He was diagnosed of renal mass by imaging studies. Inmunohistochemical investigations revealed a B-cell-type lymphoma. He received combination chemotherapy with CHOP.
Conclusions:
Primary renal lymphoma is a rare disease whose existence has been questioned, because the kidney does not normally contain lymphoid tissue. Its clinical presentation is like any other renal tumor and its definitive diagnosis is by histology. Elective treatment is chemotherapy (CHOP).