Related Experiment Video
Updated: Oct 23, 2026

Renal Capsule Xenografting and Subcutaneous Pellet Implantation for the Evaluation of Prostate Carcinogenesis and Benign Prostatic Hyperplasia
Published on: August 28, 2013
Benign fibrous histiocytoma of the renal capsule
S Kobayashi1, I Yamadori, M Ohmori
1Department of Pathology, Kagawa Medical School, Japan.
Insights
This report details the first case of benign fibrous histiocytoma originating in the renal capsule. Histological analysis revealed a distinct storiform pattern, differing from cutaneous forms.
Area of Science:
- Nephrology
- Oncology
- Pathology
Background:
- Benign fibrous histiocytoma (BFH) is a rare soft tissue tumor.
- Renal capsule tumors are uncommon, with limited reported cases of BFH.
Observation:
- A 44-year-old male presented with a tumor originating from the renal capsule.
- Histological examination showed intersecting fascicles of fibroblastic cells in a storiform pattern.
- Electron microscopy revealed intermediate filaments and membrane-bound collagen fibers.
Findings:
- The renal capsular BFH exhibited a prominent storiform pattern.
- Fewer secondary elements, such as xanthoma cells, were noted compared to cutaneous BFH.
- The tumor's deep-seated nature may influence its histological presentation.
Implications:
- This case expands the known anatomical locations for benign fibrous histiocytoma.
- Understanding the histological variations between renal capsular and cutaneous BFH is crucial for diagnosis.
- Further research may clarify the specific behavior and origin of renal capsular tumors.
Abstract:
The first case of benign fibrous histiocytoma of the renal capsule is reported in a male aged 44 years. The tumor had its point of origin in the renal capsule. Histologically, the tumor was composed of intersecting fascicles of fibroblastic cells forming a loose crisscross or "storiform" pattern. Electron microscopic studies of tumor cells revealed intermediate filaments and membrane-bound collagen fibers which continued to extracellular collagen bundles. This deep seated fibrous histiocytoma had a more prominent storiform pattern and fewer secondary elements such as xanthoma cells than cutaneous ones.
Related Concept Videos
The Retinoblastoma Gene
The first-ever tumor suppressor gene called Rb was identified in retinoblastoma - a rare eye tumor in children. In inherited forms of the disease, a child inherits one defective copy of the Rb gene, which predisposes them to retinoblastoma. However,...
External Anatomy of the Kidney
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...
Internal Anatomy of the Kidney
Anatomical Position and Dimensions
The kidneys are retroperitoneal organs positioned against the posterior abdominal wall on either side of the spine, roughly between the twelfth thoracic and third lumbar vertebrae. Each kidney is typically 10-12 cm long, 5-6 cm wide, and 3-4 cm thick, weighing about 150 grams.
Renal Cortex
The outermost region of the kidney is the...
Nephrons
Renal Corpuscle
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous capillaries...
Nephrotic Syndrome I : Introduction

