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CT attenuation of normal liver parenchyma on delayed scanning with iohexol
G Tidebrant1, P Lukes, A Wihed
1Department of Radiology, Ostra Sjukhuset, University of Gothenburg, Sweden.
Insights
Iohexol, an iodine-based contrast agent, is suitable for delayed liver CT scans. This study found increased liver parenchyma attenuation after iohexol administration, indicating its effectiveness.
Area of Science:
- Radiology
- Medical Imaging
- Hepatology
Background:
- Contrast-enhanced computed tomography (CT) is crucial for liver imaging.
- Optimizing contrast agents for delayed phase imaging can improve diagnostic accuracy.
Purpose of the Study:
- To evaluate the suitability of iohexol as a contrast medium for delayed liver CT scanning.
- To assess the attenuation values of normal liver parenchyma after iohexol administration.
Main Methods:
- Twenty patients underwent liver CT scans before, during, and 4-6 hours after intravenous iohexol injection.
- Attenuation of normal liver parenchyma was measured in Hounsfield Units (HU).
Main Results:
- Mean liver parenchyma attenuation was 62.6 HU on nonenhanced scans.
- Mean liver parenchyma attenuation increased to 78.7 HU on delayed scans.
Conclusions:
- Iohexol demonstrates potential as an effective contrast medium for delayed liver CT imaging.
- The observed increase in attenuation suggests iohexol provides adequate contrast for delayed liver visualization.
Abstract:
Twenty patients were examined with CT of the liver before, during, and 4 to 6 hours after i.v. administration of 60 g iodine (200 ml iohexol). The attenuation of normal liver parenchyma was measured. The mean attenuation of normal liver parenchyma on nonenhanced scanning was 62.6 HU and on delayed scanning 78.7 HU. It seems that iohexol is a suitable contrast medium for delayed scanning of the liver.

