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Bovine colostrums: a review of clinical uses
Insights
Bovine colostrum, rich in immune factors, offers health benefits like improved athletic performance and gut health. Specific types show promise against infections such as Cryptosporidia and H. pylori.
Area of Science:
- Immunology
- Nutritional Science
- Veterinary Medicine
Background:
- Bovine colostrum, the initial milk from cows post-parturition, possesses a distinct immunological and nutritional composition compared to mature milk.
- It is abundant in immunoglobulins, growth factors, cytokines, nucleosides, oligosaccharides, antimicrobials, and immune-modulating agents.
Purpose of the Study:
- To review the evidence supporting the beneficial effects of bovine colostrum supplementation.
- To explore the clinical utility of specific hyperimmune bovine colostrums against infectious agents.
Main Methods:
- Literature review of existing studies on bovine colostrum supplementation.
- Analysis of research on hyperimmune bovine colostrum efficacy against specific pathogens.
Main Results:
- Bovine colostrum supplementation shows potential benefits for body composition, athletic performance, and managing diarrhea in immune-deficient individuals.
- It may also alleviate NSAID-induced gastrointestinal issues and aid recovery from surgical stress.
- Hyperimmune bovine colostrums demonstrate clinical value in combating infections caused by Cryptosporidia, H. pylori, measles, rotavirus, and Shigella.
Conclusions:
- Bovine colostrum is a nutrient-dense biological fluid with diverse health-promoting properties.
- Supplementation with bovine colostrum can positively impact various physiological functions and health conditions.
- Targeted hyperimmune bovine colostrums offer a promising therapeutic approach for specific infectious diseases.
Abstract:
Bovine colostrums are the "early" milk produced by cows during the first several days post-parturition. This "early" milk has a nutrient profile and immunological composition that differs substantially from "mature" milk. Included in the nutrient profile are higher amounts of immunoglobulins, growth factors, cytokines, and nucleosides than are found in milk. Bovine colostrums are also rich in oligosaccharides, antimicrobials, and immune-regulating factors. Available evidence suggests a beneficial effect of supplementation of bovine colostrums in improving body composition, aspects of athletic performance, diarrhea in persons with immune-deficiency syndromes, NSAID-induced gastrointestinal disturbances, and aspects of the acute phase response that occurs secondary to surgery. Specific hyperimmune bovine colostrums, produced to have high neutralizing titer activity against Cryptosporidia, H. pylori, measles, rotavirus, and Shigella sp., appear to have clinical utility in conditions associated with these infectious organisms.
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