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[Lymphoepithelial cyst of the pancreas]
B Bastens1, M Golaire, J Cappelli
1Service de Médecine Interne-Gastroentérologie, Hôpital Civil, Jumet, Belgique.
Insights
A rare lymphoepithelial cyst of the pancreas was diagnosed in a 66-year-old woman presenting with abdominal pain. Surgical resection resolved her symptoms, and histological analysis confirmed the unique cyst lining.
Area of Science:
- Gastroenterology
- Surgical Pathology
- Oncology
Background:
- Pancreatic cystic lesions represent a diverse group of neoplasms and non-neoplastic conditions.
- Accurate diagnosis is crucial for appropriate management and patient outcomes.
- Lymphoepithelial cysts are exceptionally rare pancreatic entities.
Observation:
- A 66-year-old female presented with abdominal pain and unintentional weight loss.
- Imaging studies revealed a cystic lesion within the pancreas.
- The patient underwent successful surgical resection of the pancreatic cyst.
Findings:
- Microscopic examination identified the cyst lining as mature, keratinizing squamous epithelium.
- The cyst was surrounded by significant lymphoid tissue.
- This histological pattern is characteristic of a lymphoepithelial cyst, with only three prior reported cases.
Implications:
- This case adds to the limited literature on pancreatic lymphoepithelial cysts.
- The distinct histological features allow differentiation from other pancreatic cystic neoplasms.
- Further research into the histogenesis of these rare cysts is warranted.
Abstract:
A 66-year-old woman presented with abdominal pain and weight loss. Ultrasonography and computed tomography demonstrated a cystic lesion of the pancreas. After surgical resection, the patient's symptoms disappeared. Microscopic examination of the cyst lining showed mature, keratinizing squamous epithelium, surrounded by lymphoid tissue. Only three cases of this type of lesion, called "lymphoepithelial cyst", have been described previously. Histogenesis of this particular type of cyst is not well know, but can be histologically differentiated from other pancreatic cysts.