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Intra-cranial lesions in a patient with Hodgkin lymphoma
Arun S Shet1, Nabil Saba, Douglas Rausch
1Hematology and Medical Oncology Section at Hennepin County Medical Center, University of Minnesota, Minneapolis, MN 55403, USA.
Insights
Central nervous system (CNS) lesions in advanced Hodgkin
Area of Science:
- Oncology
- Infectious Disease
- Neurology
Background:
- Central nervous system (CNS) lesions in advanced Hodgkin's disease (HD) often indicate intracranial HD involvement.
- However, CNS infections can mimic neoplastic lesions.
Observation:
- A case of concurrent central nervous system tuberculosis in a patient with stage III E Hodgkin's disease is presented.
- This represents the first reported instance in English literature.
Findings:
- The study highlights the diagnostic challenge posed by CNS lesions in Hodgkin's disease.
- Concurrent CNS tuberculosis can present similarly to intracranial HD.
Implications:
- Early recognition and differentiation between neoplastic and infectious CNS lesions are crucial for appropriate management.
- This case underscores the importance of considering infectious etiologies in immunocompromised patients with CNS involvement.
Abstract:
Central nervous system (CNS) lesions in newly diagnosed, advanced Hodgkin's disease (HD) commonly suggest intracranial involvement with HD. However, occasionally this could be the result of a CNS infection. We report a case of concurrent CNS tuberculosis in a patient with stage III E HD the first reported in the English literature. Management of this case and the literature pertaining to infectious complications of HD are reviewed.
