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Published on: October 30, 2013

Cytologic features of recurrent lymphoma involving the urinary bladder

Adam M Quinn1, Robert Flanigan, Anna Sienko

  • 1Department of Pathology, Loyola University Medical Center, Maywood, Illinois 60153, USA.

Diagnostic Cytopathology
|September 7, 2004
PubMed

Insights

Diagnosing bladder lymphoma through urine cytology is rare. This case highlights key cytomorphological features of diffuse large B-cell lymphoma in urine, emphasizing the need for immunohistochemistry.

Area of Science:

  • Uropathology
  • Cytopathology
  • Hematopathology

Background:

  • Lymphoma involvement of the urinary bladder is uncommon, often lacking typical genitourinary symptoms.
  • Cytologic findings of bladder lymphoma are infrequently reported in medical literature.

Observation:

  • A 77-year-old male presented with recurrent urinary tract infection and hematuria.
  • Bladder barbotage specimen revealed diffuse large B-cell lymphoma with immunoblastic morphology.

Findings:

  • Detailed cytomorphological features of lymphoma cells within the urine sediment were described.
  • Differential diagnoses for atypical cells in urine were discussed.

Implications:

  • This case underscores the diagnostic utility of urine cytology for detecting bladder lymphoma.
  • Correlating cytologic findings with immunohistochemical analysis is critical for accurate diagnosis and patient management.

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