Related Experiment Video
Updated: Aug 8, 2026

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
Published on: May 1, 2015
Submucoal lymphoid aggregates of the lower lip in a 10-year-old boy
Yuk-Kwan Chen1, Yee-Hsiung Shen, Cheng-Chung Lin
1Department of Oral Pathology, School of Dentistry, Kaohsiung Medical University, 100 Shih-Chuan 1st Road, Kaohsiung, Taiwan, ROC.
Insights
A rare case of lymphoid hyperplasia mimicked a mucocele in a young boy's lower lip. This finding highlights the importance of accurate diagnosis in pediatric oral lesions.
Area of Science:
- Oral Pathology
- Pediatric Dentistry
- Head and Neck Surgery
Background:
- Lymphoid hyperplasia is a benign proliferation of lymphoid tissue.
- Mucoceles are common benign cysts in the oral cavity, typically caused by minor salivary gland duct obstruction.
- Distinguishing between these conditions is crucial for appropriate management.
Observation:
- A 10-year-old boy presented with a lesion on his lower lip.
- The lesion clinically resembled a mucocele.
- Histopathological examination revealed lymphoid hyperplasia.
Findings:
- The case demonstrated an unusual presentation of lymphoid hyperplasia mimicking a mucocele.
- This highlights the potential for varied clinical appearances of benign oral conditions.
- Accurate histopathological diagnosis is essential.
Implications:
- This case underscores the need for thorough differential diagnosis in pediatric oral lesions.
- It may prompt clinicians to consider lymphoid hyperplasia in the differential diagnosis of lip lesions presenting as mucoceles.
- Further understanding of such presentations can improve diagnostic accuracy and patient care.
Abstract:
We report an unusual case of lymphoid hyperplasia that looked like a mucocele in the lower lip of a 10-year-old boy.
Related Concept Videos
Development of the Lymphatic System
The first lymph sacs to form are the paired jugular lymph sacs located at the junction of the internal jugular and subclavian veins. From these sacs, lymphatic capillary plexuses extend to the thorax, upper limbs, neck, and head, eventually forming lymphatic vessels. Each jugular lymph sac maintains a...
Histology of the Small Intestine
The intestinal lining features transverse folds called circular folds, each housing fingerlike projections known as intestinal villi. These villi are covered by a layer of simple columnar epithelium, also referred to as...
Appendicitis

