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B cell lymphoma: a case with localized involvement of the prostate on F-18-FDG examination
Veronica Solis1, Ronald J Rosenberg, Richard P Spencer
1Division of Nuclear Medicine, Diagnostic Imaging and Therapeutics, University of Connecticut Health Center, Farmington, CT 06030-2804, USA.
Insights
Positron emission tomography (PET) with F-18 FDG successfully localized B cell lymphoma to the prostate in an elderly man presenting with urinary retention. The imaging confirmed the disease was confined to the prostate gland.
Area of Science:
- Oncology
- Nuclear Medicine
- Radiology
Background:
- B cell lymphoma can present with urinary symptoms.
- Accurate staging is crucial for effective lymphoma treatment.
Observation:
- An 80-year-old male patient presented with urinary retention.
- Prostate biopsy confirmed B cell lymphoma.
- F-18 FDG PET/CT was utilized for staging.
Findings:
- Increased F-18 FDG uptake was observed in the prostate bed.
- Noncontrast CT demonstrated intact surrounding fat planes.
- These findings indicated localized disease within the prostate.
Implications:
- F-18 FDG PET/CT is effective for staging localized prostate B cell lymphoma.
- This imaging modality aids in treatment planning.
- Early and accurate diagnosis improves patient outcomes.
Abstract:
An 80-year-old man had symptoms of urinary retention. Biopsy of the prostate revealed B cell lymphoma. To evaluate the extent of the disease, an F-18 FDG study was performed with positron emission tomography/computed tomography (CT). One hour after intravenous administration of 18.5 mCi F-18 FDG, imaging was carried out from the skull base to the upper thigh. An area of moderately increased activity was noted within the prostate bed. A noncontrast CT, for attenuation correction and anatomic localization, revealed maintenance of fat planes around the prostate, indicating disease localized to that organ. Hence, a B cell lymphoma had been localized to the prostate.
